Pay in 4 interest-free payments of $20.00 Learn more
Ships within 48 hours · Estimated delivery Aug 5 - Aug 10
Shipping Condition: Room temperature in continental US
consistent with an essential role for HECT ligase activity in mammalian cells
Smiles: COC1=CC=CC=C1C(=O)NC1=CC2=C(C=C1N1CCCC1)N(C)C(=O)N2C
It shows more than 100-fold selectivity for mTOR relative to PI3Kα
2010 Sep 22
Bedaquiline Catalog No.:M8161-2 Shipping Condition: Room temperature inBedaquiline, also known as TMC207 and R207910, is a diarylquinoline anti tuberculosis drug, which was discovered by a team led by Koen Andries at Janssen Pharmaceutica. Bedaquiline blocks the proton pump for ATP synthase of mycobacteria. ATP production is required for cellular energy production and its loss leads to cell death, even in dormant or nonreplicating mycobacteria. It is the first member of a new class of drugs called the diarylquinolines.